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Citation Information

Type Journal Article - Trends in parasitology
Title Estimating the needs for artesunate-based combination therapy for malaria case-management in Africa
Author(s)
Volume 19
Issue 8
Publication (Day/Month/Year) 2003
Page numbers 363-369
URL http://cghed.ei.columbia.edu/sitefiles/file/PublicationPDFs/Estimated need ACTs.pdf
Abstract
Because of inadequacies in national health information systems, the volumes of drugs required to support an effective policy transition toward artesunate-based combination therapy (ACT) are unknown for most African countries. A series of national surveys and population projections have been used to estimate the age-structured fever burden among 41 malaria endemic countries in Africa. Under present fever-management guidelines, commodity costs and internationally agreed coverage targets, the financial resources to meet the needs of ACT in most African countries are huge. Between US$1.6 billion and US$3.4 billion per annum must be found to give Africa the chance to consider a drug policy based on ACT. Substantial reductions in these costs would be achieved through more effective targeting of resources – only 20% of drugs would be required to manage fevers among the most at-risk pediatric patient populations. Better diagnostics would also be an important consideration for a new ACT policy in Africa.

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