Objective: To explore Palestinian women's knowledge, perceptions, and attitudes towards HIV/ AIDS.\n\nMethods: Data used in this study were collected as a part of the Demographic and Health Survey (DHS) 2004 in the Occupied Palestinian Territory (OPT).\n\nResults: Most of the women in the OPT (93.4%) had heard of AIDS. They had fair general knowledge of HIV/AIDS prevention methods and transmission. TV was the main source of information about HIV/AIDS. Among the determinants of HIV/AIDS knowledge identified by this study were education, region, and locality.\n\nConclusion: A research-informed policy concerning HIV/AIDS prevention should be formulated\n